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DeCS
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Descriptor English:
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Pregnancy-Associated Plasma Protein-A
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Descriptor Spanish:
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Proteína Plasmática A Asociada al Embarazo
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Descriptor Portuguese:
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Proteína Plasmática A Associada à Gravidez
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Synonyms English:
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IGFBP-4 Metalloproteinase
IGFBP-4 Protease
IGFBP-4-Specific Proteinase
Insulin-Like Growth Factor-Dependent IGF Binding Protein-4 Protease
Insulin-Like-Growth Factor Binding Protein-4 Protease
PAPP-alpha
Pregnancy Associated alpha Plasma Protein
Pregnancy-Associated alpha-Plasma Protein
IGFBP 4 Metalloproteinase
IGFBP 4 Protease
Insulin Like Growth Factor Binding Protein 4 Protease
Insulin Like Growth Factor Dependent IGF Binding Protein 4 Protease
Metalloproteinase, IGFBP-4
PAPP alpha
Pregnancy Associated Plasma Protein A
Protease, IGFBP-4
PAPP-A
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Tree Number:
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D08.811.277.656.300.480.632
D08.811.277.656.675.374.632
D12.776.780.700
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Definition English:
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A product of the PLACENTA, and DECIDUA, secreted into the maternal circulation during PREGNANCY. It has been identified as an IGF binding protein (IGFBP)-4 protease that proteolyzes IGFBP-4 and thus increases IGF bioavailability. It is found also in human FIBROBLASTS, ovarian FOLLICULAR FLUID, and GRANULOSA CELLS. The enzyme is a heterotetramer of about 500-kDa. |
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History Note English:
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2004 (1996)
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Allowable Qualifiers English:
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Record Number:
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11686
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Unique Identifier:
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D011266
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Occurrence in VHL:
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Similar:
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DeCS CID-10 LILACS
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